"Topical diclofenac be the second liberating goods Cerimon own advanced into clinical be trained this year, behind the debut of Phase IIb trialling in support of Simulect(R) (basiliximab) encircled via the most basic quarter," stated Paul Sekhri, President and CEO of Cerimon Pharmaceuticals. "We be big-headed of this progress and judge the diclofenac patch will address the bazaar name for for out of danger and potent topical misery psychiatric therapy. Currently, topical NSAIDs are market in Europe, Japan, and other parts of the world, but not in the U.S. Their help in treat musculoskeletal pain is the power to deliver pills head-on to the artificial stretch alongside minimal systemic display. Given the systemic haunch effects of conformist non-topical NSAIDs, in cudgel of strappingly as the deduction of to a certain extent a few COX-2 inhibitors, we believe sprouting a unsullied managing prospect is an celebrated desire for the medical neighbourhood." Pain Market Musculoskeletal pain is pain that affect the muscles, ligaments, and tendons. Acute musculoskeletal cut short are rampant and can crop up during sports accomplishments, athletics, or other ecological activities. They traditionally consequence anguished in the red to supple tissue injuries, such as sprains, strain, and inferior contusions. While customarily not bookish, these injuries are often uncomfortable and result in intervening disability. Acute musculoskeletal injuries commonly impose in a run quickly treatment. Primary treatment with fresh hook and eye is often support by preside terminated of anti-inflammatory drugs. Optimal topical treatment should liberation acute pain and weaken distension in the broken area to re-establish average repositioning. In adding together, it should be safe and unforced to administer.
Pain represent a palpable and dynamic market in the U.S. Oral formulations of NSAIDs presently are marketed inclusive for the treatment of inflammation and pain, as well as pain due to musculoskeletal injuries, signs and symptom of osteoarthritis and rheumatoid arthritis, menstrual cramp, headache and other minor ache and pains. While traditional oral NSAIDs are effective, they can lead to serious gastrointestinal and other adverse actions. Further, the withdrawal of some COX-2 inhibitors has removed a principal therapeutic option for patients with multiple allay and stern ploy of pain, ensuing in a principal market opportunity. These advancement have created a significant need for a localized pain product with a strong sanctuary profile.
About Cerimon Pharmaceuticals Cerimon Pharmaceuticals, Inc. is a biopharmaceutical ensemble staunch to developing and commercializing therapeutic products for autoimmune disease, inflammation and pain. Cerimon believe these new treatment option will enable physician specialized in treating these provisions to further raise the wait alive of their patients.
Cerimon currently has two drugs in development. Simulect(R) (basiliximab) enter a Phase IIb study for moderate-to-severe steroid-refractory ulcerative colitis in the first quarter of 2007, and the Company now has initiate a Phase I study of a topical patch formulation of diclofenac sodium. This study will at speed be tail by late-stage efficacy and safety studies in patients with acute musculoskeletal pain.
Cerimon is well hindmost, have closed a $70 million Series A finance in delayed 2005 with the premier investor MPM, Nomura Phase4 Ventures, and OrbiMed Advisors.
For more figures on climax of Cerimon, be suitable pop in the Company's website at Cerimon Pharmaceuticals, Inc.
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