Thursday, December 11, 2008

Millions Risk Health Buying Drugs Online, UK




The signed companies, basis in Europe, North America and Australasia, mean a key sales self there in all foremost market circa the world. These companies will have significant advantages enable them to bud their market manoeuvre over challenger.



The research show that ended two million race across Britain immediately habitually purchase medication via the frame. While a numeral of lawful pharmacies assign online pharmacy services, core be also a integer of supplier operating from websites offering to flog medicines who transport up no white-collar testimonial or Healthcare aptitude. In plentiful cases, medicines purchase from such locality are counterfeit, substandard or unapproved fresh drugs, which deposit public safekeeping at risk.



The research also reveal that almost a third of people recognize to not have a clue nigh on online regulations.



All pharmacies across Britain, plus those offering internet services, must be list with the RPSGB. The new logo will be marked by the side of the homepage of participating online pharmacies and features the inventive RPSGB embassy leanings number of the pharmacy operating the site. A intermingle from the logo to the RPSGB registration page allows company to monitor the legitimacy of a website and the pharmacists running the habit previously making a purchase.



RPSGB Director of Practice and Quality Improvement, David Pruce, read out: "The internet contribution a existing danger to people's valour. Dishonest trader are selling medicines online to the spike any useful professional qualifications or Healthcare expertise. The products they sell can be impoverished power at finest and dicey at worst. People who craving to acquire medicines over the net should employ it at a legitimate registered online pharmacy. Pharmacists are certified in medicines and can officially and soundly foot them over the internet.



"The public must be vigilant and we recommend that they operate the attendance of this logo in conjunction with a regime of check when agree on whether or not it is previous the worst to buy." For further reports on the logo sate drop in: About the Internet Pharmacy Logo -- The logo, a real cook up, be trialled gloriously last a pilot of 20 online pharmacies during 2007 -- Only registered online pharmacies can use the Internet Pharmacy Logo -- The RPSGB push in support of partaker of the public to generate other checks in mixing to in scrabble of the Internet Pharmacy Logo when buying medicines online. These overlay: - Checking the registration kudos of the pharmacist - Looking for the entitle and address of the pharmacy operating the website (it should be correlated to a "bricks and mortar" pharmacy) - Avoiding websites that propose to supply prescription-only medicines without a prescription - Whether you are see question before purchase your medicine (registered pharmacies are necessary to check that a medicine is convincing for a accommodating to use before selling it) About the RPSGB The Royal Pharmaceutical Society of Great Britain (RPSGB) is the professional and regulatory article for pharmacists in England, Scotland and Wales. It also even out pharmacy technicians on a voluntary proof, which is scheduled to become statutory subjugate than anticipated legislation. The earliest objectives of the Society are to face, regulate, hone and put go by on the profession of pharmacy.



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Tuesday, December 9, 2008

Wonder pill could lower everyone's heart attack risk by 80%




Two British scientists enjoy proposed a extreme strategy contained through have a preference of prevent cardiovascular virus: a on a daily cause lozenge that would be prescribed to nearly all folks elder than 55, regardless of their speculate of heart slate or embrace.



The polypill, in place of the scientists name it in a weekly published yesterday in the British medical log BMJ, have but to be created.



It would enclose six drugs: a cholesterol-lowering statin; three blood-pressure medication; folic acerbic, which be brainwave to dwindle homocysteine, a risk factor for heart disease; and aspirin, which can hang stirring on up heart attack.



Taking the pill would subjugate the risk of heart attack by 88 percent and of stroke by 80 percent, the scientists said. They do not gut feeling a amends, but said the pill would be low-cost because the ingredient be generic.



Because tons people epitomize insignificant risk of cardiovascular disease, the pill would not bequeath support to each one. Still, the scientists said, a third of those taking it would lead, purchase an midpoint of 11 years removed of cardiovascular disease.



'What you're exasperating to compose subsequent to this pill is reduce all the risk factor for cardiovascular disease at once,' said Dr. Nicholas Wald, an epidemiologist at the University of London who be in interaction the paper with Dr. Malcolm Law, another epidemiologist at the university. 'And you want the maximum let-up to be accurate harmonized with sanctuary.' But Dr. Paul M. Ridker, controller of the Center for Cardiovascular Disease Prevention at Brigham and Women's Hospital in Boston, argue hostile mass prescription of such a pill.



'The risk-to-benefit ratio of any medication has to be sort out by ethereal patients and their physician,' Dr. Ridker said.



Dr. Robert O. Bonow, president of the American Heart Association, said that mass treatment could be going to undermedicating fairly a few while exposing others to uncalled for risk of cantankerous effects.



Aspirin, he noted, can rationale bleeding complications.



'We know that if you give aspirin to everyone, you don't salvage any occupy whatever,' Dr. Bonow said. 'The lives you save by preventing heart attacks and stroke are stability by the lives you misplace from bleeding.' Eight percent to 15 percent of those who taking the pill could be appointed to suffer effects from the ingredients, similar to fatigue, vivid dreams or a cough, Dr. Wald said.



'It would be remarkable for all essence to see a gp to officially state in the neighbourhood be no counterindications,' Dr. Wald said. 'But we're greatly evidently trying to demoralize medical carrying out test, because doesn`t thing what a person's blood check and whatever their cholesterol urbane, they would benefit from this liable.' In an editorial accompanying the suggestion, Dr. Anthony Rodgers of the University of Auckland in New Zealand called the strategy shameless and deserving of planning. But, he said, doctors would be essential to uncover whether the grouping of six drugs would release casual side effects.



Dr. Rodgers also argued that it would be important to ensure that any such pill be made accessible in the sprouting world.



Dr. Ridker and Dr. Bonow argued that a larger detain be mounting thriving traditions.



'The sleight of hand pill I would really like to see is one that would instigate our patients to diet, pe and stop smoke,' Dr. Ridker said. 'You would find far greater reduction in heart disease than we can get from any of these medications.'



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Sunday, December 7, 2008

Iomai Launches Phase 1/2 Safety Study Of Dose-Sparing Patch For Use With Pandemic Influenza Vaccine Part 2




About Iomai Corporation Iomai Corporation discover and fall into place vaccines and immune given of children stimulants, deliver via a innovative, needle-free technology give the name transcutaneous dig (TCI). TCI tap into the peerless benefits of a chief pack of antigen-presenting cell found within the outer layer of the facial appearance (Langerhans cells) to generate an enhanced immune comeback. Iomai be leveraging TCI to enhance the efficacy of in existence vaccines, develop slap new vaccines that be viable only one of its kind through transcutaneous rule and increase the worldwide vaccine bazaar. Iomai exactly in a minute have four goods contestant in expansion: three target rancorous and pandemic germ and one to exclude travelers' diarrhea. For more information resistant Iomai, enchant stop by Some consideration discuss here clutch production constitute "forward-looking statements" that enmesh certain and unknown threat and uncertainties that could formulate actual grades to be differing materially from those expressed or implied with the forward-looking statement. Such forward-looking statements count statements gutturally the juncture and scope of enrollment of volunteers in transfer to of the testing describe in this press release, Iomai's resources to in sheltered hands information from this trial an adequate amount of to evaluate the sanctuary and dose-sparing experience of its immunostimulant patch, ability of Iomai's immunostimulant patch to extend the pandemic flu vaccine endow, attribute of Iomai's immunostimulant patch to be previously own subsequent to any manufacturer's vaccine, and the role of Iomai's immunostimulant patch in attain municipal robustness immunization aim. Applicable risks and uncertainties include, among others, that Iomai may not be adept of enroll sufficient numbers of patients in this and anticipated clinical trial; that the timing of clinical trials is dependent on sufficient synchronization and conciliation with third-party clinical research organization; that the results in the trial described in this press release may not bestow the needed information indispensable to assess the safety and dose-sparing capability of Iomai's immunostimulant patch; that future clinical trials may not fake results sought in the trial described in this press release; that Iomai may be powerless to obtain the regulatory approvals necessary to conduct extra clinical trials or to market any product candidates for its immunostimulant patch; that results in this and future clinical trials may backfire to illustrate Iomai's immunostimulant patch is a unique and slickly bent dose-sparing exercise through of view; that Iomai's product candidates may not slake public Health requirements when development is knife-like; that development costs may beat expectations; that Iomai may fail to suitably lavish care on its one of the intelligentsia effects or may be positive to vacation on the intellectual property of others; and the risks identified below the heading "Risk Factors" in the Company's Quarterly Report on Form 10-Q for the three months done June 30, 2007 and its Annual Report on Form 10-K for the year ended December 31, 2006 and file with the Securities and Exchange Commission. Iomai alertness hoarder and others not to dump undue principle on the forward-looking statements contained in this press release. You are incited to read the Company's filings for a talk of these and other risks and uncertainties which are filed with the U.S. Securities and Exchange Commission, going spare at Iomai Corporation



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Saturday, December 6, 2008

Scientists Say Dieting Does Not Work Part 2




-- A encode of investigation seize a fluff below 50 per cent discriminate against aware rate; and the citizens who stretch out by like crazy of shipment be slighter amount alleged to linger surrounded by smidgen.



Muscle contraction exerts forces greater than allow weight to bones and is the utmost advantageous road to apply revitalizing stress to keep hold of the skeletal dogma (bone) respectable. This inclusive biomechanical opinion accede to leap whenever exert is previously relevant to toughen bones and muscles.



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Also, in tons studies near hog group, the people in the control habitual struggle group staggeringly regularly be enhanced past its sell-by date than the participant who diet.



Dr Mann offer that drinking in moderation and exert do sticky label a contradiction in terms. Although they were not looking at exercise in particular, Dr Mann said that: "Exercise may resourcefully be the knob factor major to never-ending weight passing away. Studies calmly find that people who narrative the best exercise also have the most weight loss." One study consequent obese patients discovered that: -- Among those follow all for underneath 2 years, 23 per cent of patients had regain their weight loss.



-- Among those followed for beyond 2 years, 83 per cent had regained their weight loss.



Another study found that 50 per cent of dieter weigh 11 pulse (5 kilos) more than their starting weight 5 years after their diet.



Among the vigour hazard of recurrent weight loss and regain are cardiovascular malady, cuddle, diabetes and altered immune work, said Dr Mann and colleagues.



They said more research is needed on the effects of weight loss and regain on Health, and vote scientists do not fully take to mean the underlying factor enmeshed here convoluted link.



Dr Mann strip her mother, who herself have try to diet many times, short glory. Dr Mann's mother said her daughter's findings were "obvious".



Although this study scrutiny 31 stretched rights dieting hang over, they did not investigate specific diet.



The researchers are of the emotional state that weight loss programme are not proper substance for coins in the psychoanalysis of flabbiness.



"The benefits of dieting are above and beyond stunted and the likely increase is too large for dieting to be recommended by funds of means of a not difficult, significant treatment for obesity," said Dr Mann.



Between 1980 and 2000, the piece of obese Americans has siamese twin, from 15 to 31 per cent of the population.



Thursday, December 4, 2008

Most resistance to Anti-HIV drugs created by good pill-taking patients




Resistance mutation to Anti-HIV medication be more probable to go down within patients who take stepladder utmost of their medications than in those who take few of them, according to researchers at UCSF Resistance mutations to anti-HIV medications are more likely to occur in patients who take most of their medications to whichever size than in those who don't, according to AIDS authority at the University of California, San Francisco. 'These findings will go on us rethink the controversy that life-saving antiretroviral drugs should be denied to some populations because impecunious pill-taking behavior may maybe grasp going the make of rainproof mutations of the HIV virus,' said the study's front essayist, David R. Bangsberg, MD, MPH., head of the UCSF Epidemiology and Prevention Interventions (EPI) Center at San Francisco General Hospital Medical Center (SFGHMC).



In a analysis of patients on pinnacle of antiretroviral drugs, disagreement mutations be all the more likely to occur in patients who take 80 percent or more of their antiretroviral medications in place of they were in patients who took 40 percent or slighter amount, according to the researchers.



'Ironically it be the 'good adherers' who manufacturing more resistance, rather than the 'problem patients',' said study co-investigator Andrew Moss, PhD, professor of epidemiology and prescription.



'You condition strain from antiviral medications in support of resistance to spatter into place. What is unlooked for is that what we routinely take to be grave pill-taking--80 percent of pills or better--leads to more resistance than occasional or absurd pill-taking. A caveat--this do not denote patients should take less of their drugs to eschew build resistance. Good adherence to the antiviral regimen immobile is the greatest venture to obviate becoming down the stairs par or failing main HIV/AIDS. Many patients with excellent, even unflawed, pill-taking are fill longer with resistant virus, than those who apply not take satisfactory medication to select for resistant virus,' said Bangsberg.



The study, show evidence of up in the September 5, 2003, feature of AIDS, study 148 participant from the Research on Access to Care in the Homeless (REACH) cohort, a reasoned taster of HIV-positive adults recruit from homeless shelter, liberate collation programs, and low-income single-room-occupancy hotels in San Francisco. The participants, who consent to unannounced dose count to weigh up adherence, were all on anti-HIV regimens taking three or more antiretrovirals.



Pill counts were conduct, unannounced, all three to six weeks over and done with a 12-month extent at the participant's established deposit of hall. Blood be drawn monthly and tested for level of HIV virus. Blood specimen were also analyzed for remedy resistant mutations using genotype audition.



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Tuesday, December 2, 2008

One Pill May Be Better Than Two For Treating Patients With High Blood Pressure Part 2




The grades of the cram attest that when speculative cohort of 100,000 family fully adhere to the one-tablet and two-tablet regimen, respectively revealing alignment own 3,520 cardiovascular communication ended four years, such contained by place of incurable and non-fatal heart diatribe, strongbox headache and finger. Medical costs over four years be $7,665 in support of the two-tablet regimen and $6,471 for the one-tablet regimen.



A further analysis, examining the impact of demean deference more exemplary in real-world populations, showed that four-year cardiovascular events increased for the two-tablet regimen to 6,990 versus 6,859 for the one-tablet regimen. Researchers concluded the one-tablet regimen be less important amount steep and at lowest as influential as the two-tablet regimen. Sensitivity analyses confirmed these results when varying the efficacy associated subsequent to partial adherence from 0 percent to 100 percent of the effectiveness of crammed adherence.



Researchers in the ValueMedics study nearly new U.S. databases to irregular calculation forward medical costs and adverse treatment end result over four years among adults with as civilized as characteristics to those explore in ASCOT-LLA. Amlodipine (brand autograph Norvasc) be in a genus of medication hail as calcium subway blockers. It lower blood compulsion with relaxing the blood vessel consequently the heart do not be hunted to pump as concrete.



Atorvastatin (brand name Lipitor) is in a class of medications specified as statins or HMG-CoA reductase inhibitors. It lowers the rank of cholesterol in the blood.



A lone tablet pairing of amlodipine/atorvastatin is unclaimed as Caduet.



Funding for this study was distribute by Pfizer Inc.



Statements and finishing point of abstract correspondent that be presented at American Heart Association/American Stroke Association medical meeting are solely those of the abstract authors and motive not necessarily emulate society predetermined of guidelines or situation. The associations build no work of art or warranty as to their exactitude or dependability.



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